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These symptoms range from common to signs of an emergency: Common Candida Die-Off Symptoms Nausea Headache Brain fog Skin rashes or itching Muscle and joint pain Chills and low-grade fever Swollen glands Fatigue and irritability More Severe Candida Die-Off Symptoms Anxiety and depression Heart palpitations Vasodilation and skin flushing Sugar cravings Oral thrush and sore throat Sleep disturbances Signs to Seek Emergency Help Difficulty breathing Sudden severe rash or blisters Swelling of the face, tongue, or throat Fainting or a weak pulse What Causes Candida Die-Off Symptoms