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Metal ions Life Sci

Several lines of evidence highlight the critical role of non-TG lipids, such as SFAs, free cholesterol and ceramides, in the progression to NASH by triggering inflammation, cellular damage and fibrogenesis

Abstract Despite its position as the first-line drug for treatment of type 2 diabetes mellitus, the mechanisms underlying the plasma glucose level-lowering effects of metformin (1,1-dimethylbiguanide) still remain incompletely understood