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The new regulation now includes items such as synthetic nicotine pouches and disposable vapor products, which were not previously taxed

Cigarettes are cheaper upfront, but also more addictive

49 Moreover, in vitro incubation of human monocyte-derived DCs with cigarette smoke extract suppressed the lipopolysaccharide-induced upregulation of CD40, CD80, CD86, and CCR7

Could Maintain Connections to Smoking: Although harm reduction is the aim, some people may find it more difficult to completely quit smoking if they use vapes that taste like cigarettes because they unintentionally reinforce associations with traditional smoking