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Marieh Honarmand, Alireza Nakhaee, and Mohammad Moradi, Comparison of Salivary Cotinine Concentrations in Male Smokers and Smokeless Tobacco Users, 2018

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The question then becomes, how to build a mathematical model of the mechanisms that link a change to tobacco and/or alcohol policy to its outcomes in the light of our understanding of the system

It found that, over time, people who smoked saw their social contact reduce, and they became less socially engaged and more lonely, compared to non-smokers