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Trichome density: Trichomes are the tiny crystal-like structures found on the surface of cannabis buds

But is the by-product of combustion that causes harm because the smoke contains multiple carcinogens, and leave deposits on the respiratory systems that severely impact on cardiovascular and respiratory function

Moreover, available data support the hypothesis that caffeine assumption and cigarette smoking may show synergistic effects on the hemodynamic status [10, 11]

Researchers evaluated the association between baseline e-cigarette use and subsequent cannabis use over three 12-month follow-up periods (Wave 1 to Wave 2, Wave 2 to Wave 3, and Wave 3 to Wave 4) while accounting for the survey wave, individual characteristics, and state recreational cannabis legalization status