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In a rat Alzheimers model induced by chloroindoleamine (CHL), Y maze and radial arm maze tests confirmed that nicotine significantly improved the spatial memory deficit, and restored the antioxidant capacity of superoxide dismutase in the rat hippocampus, showing potential properties for memory improvement (Hritcu et al., 2017)

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Pesticide methoxychlor promotes the epigenetic transgenerational inheritance of adult-onset disease through the female germline