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Quick memory phrase: Loops flush, Thiazides shower, Spiro saves bananas, Aceta climbs the attic. The Clinical Reality: Nephron Sites of Action While the house is fun, pharmacy techs also need to know the actual sites of action in the nephron : Proximal Tubule Acetazolamide (Carbonic Anhydrase Inhibitor) Loop of Henle Furosemide (Loop Diuretic) Distal Tubule Hydrochlorothiazide (Thiazide Diuretic) Collecting Duct Spironolactone (Potassium-Sparing Diuretic) This matters because side effects and monitoring parameters often come directly from where the drug acts

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