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Many epidemiological studies have been conducted on the association between smoking and atherosclerosis, and it is clear that smoking increases the incidence and mortality of diseases, including ischemic heart disease and cerebrovascular disease that are based on atherosclerosis 3 , 4)

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and Yee Ah Tye, an English-speaking merchant who had been nearly destitute when he first arrived, but now owned his own mining company and had a hundred men in his employ

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