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Although the study contributes data to help answer this question, the findings will need to be confirmed in other settings and contexts, she cautioned, and there are features of the study that caution against a broad interpretation of the effectiveness for e-cigarettes for smoking cessation. Broader Context of the Findings The clinical trial enrolled 886 adult smokers (median age 41) who sought help with quitting cigarette smoking through the National Health Services (NHS) stop-smoking service, which is available for free to smokers in the United Kingdom

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Based on prior studies demonstrating that smoking reduces a marker for neuroinflammation in HIV- individuals, we hypothesized that HIV+/Smok+ individuals would have less neuroinflammation and better cognitive control than HIV+/Smok- individuals