In 2015, Barack gave his best crack at dad jokes during the annual ceremony, telling the crowd (via Daily Mail): "It is hard to believe that this is my seventh year of pardoning a turkey," adding, "Time flies, even if turkeys don't." The line earned him a laugh from Sasha, who admitted, "That was good, that was good." It's clear that the sisters' idea of a fun Thanksgiving morning doesn't involve meeting turkeys being given a free pass, and Barack admitted as much during his speech, saying, "They do this solely because it makes me feel better." It seems Malia and Sasha withstood all the dad jokes they could handle, however, as the two sisters were noticeably absent from the 2016 turkey pardoning
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In this Perspective, we view this axis as an important mechanistic link between smoking-related exposure and the persistent inflammatory microenvironment that drives synovitis, cartilage damage, and OA progression