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Cardiovascular measures of heart rate, heart rate variability and blood pressure were unchanged in all groups. In people, the methacholine challenge involves inhaling a dose of the chemical methacholine, which slightly narrows the airways and shows how reactive or responsive the persons lungs are to things in the environment

Most people who use electronic cigarettes also smoke conventional cigarettes at some stage during their smoking career

This highlights the importance of addressing vaping practices and underlying motivations, alongside awareness of health risks, when developing interventions aimed at reducing nicotine dependence in this population

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