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Enzymatic conversion of benzo(a)pyrene leading predominantly to the diol-epoxider-7, t-8-dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene through a single enantiomer of r-7, t-8-dihydroxy-7,8-dihydrobenzo(a)pyrene

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This is one approach scientists have used to find genes associated with smoking, but this is the first time this approach has been able to reveal genes associated with tobacco use disorder