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PG can also be metabolized to methylglyoxal by alcohol dehydrogenase enzymes expressed in the airway epithelium 20

Gender-specific effects of the catecol- O -methyltransferase Val158Met polymorphism on cognitive function in children

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At the same time, the smoking-generated CO binds with haemoglobin and myoglobin, reduces arterial O2 blood saturation, compromises the efficiency of respiratory enzymes, and causes dysfunction of the O2 production, transportation and delivery system, especially during exercise, substantially reducing the functional capacity and the performance of the circulatory system