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Current Addiction Reports [Internet]

Smoking tobacco causes exposure to a lethal mixture of more than 7,000 toxic chemicals, including at least 70 known carcinogens that can damage nearly every organ system in the human body

Cheryl Warsh states: The onset of the Great Depression dampened the market for the sale of material commodities, but not necessarily the sale of the image[2] As a result, many economists and advertisers acknowledged the potential growth of the nicotine industry that could be produced by targeting and selling tobacco products to women

Given potential issues with the supply and demand of SyN, in addition to the higher associated costs, there is the concern of nicotine or nicotine products being sold that contain a mixture of TDN and SyN