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Furthermore, the aerosol of a cMRTP should have a reduced effect on the intracellular GSH pool and ROS generation compared to cigarette smoke

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A meter to measure carbon monoxide in breath can be used to guide treatment

Specifically, the analysis predicts that implementation of key tobacco policy changes could lead to roughly 100,000 fewer cancer cases, 730,000 fewer hospitalizations, and 170,000 fewer deaths attributed to smoking in the first two decades following policy change as well as saving over $24 billion in smoking-attributable medical costs and increasing productivity by over $100 billion