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This cholinergic activation mediates arousal and vigilance, producing nicotine-like psychostimulant effects

27 Experiencing or witnessing trauma in childhood (such as childhood sexual or physical abuse or interpersonal violence) is also associated with an increased likelihood of smoking uptake

Youth Tobacco Use Continues to Decline Across All Product Types in 2022, One in Five Youth Still Use Tobacco

Current evidence indicates that all commercially available forms of Nicotine Replacement Therapy (NRT) including gum, transdermal patches, nasal sprays, inhalers, and sublingual tablets/lozenges enhance the likelihood of successfully quitting smoking