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The combined effects of local mucosal irritation and cellular damage due to the numerous carcinogenic substances found within cigarettes create the ideal environment for developing cancerous changes within cells

This process uses (already one-time fermented) air-cured or flue-cured tobaccos like Virginia, burley, Maryland or any combination of these three types

When the ban on TV cigarette advertising deprived the tobacco industry of its principal means of persuading the customer directly, the industry, adapting itself to circumstances, turned around and placed far greater emphasis than formerly on salesmanship where it counted most at the spot where the customer turned up to buy

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