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Not much longitudinal work has been done to see what proportion of youth vapers persist or escalate vs

Macrophages pigmented smokers macrophages in respiratory bronchioles and neighbouring alveoli, containing granular, yellow-brown cytoplasmic pigments References and Links Barnes P , Mechanisms in COPD compared with asthma semantic Scholar Benjamin, R MD, MBA VADM, USPHS, Surgeon GeneralExposure to Tobacco Smoke Causes Immediate Damage: A Report of the Surgeon General Bohadana A et al Mechanisms of chronic airway obstruction in smokers Respiratory Medicine Volume 98, Issue 2, February 2004, Pages 139-151 TCV

[1] The report estimates that half a million Americans die from smoking every year, and this number has not changed in a decade

What does WHO recommend