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When a compound is ingested orally, it goes through the digestive system and is processed by the liver before it ever reaches the rest of the body

doi: 10.1016/j.freeradbiomed.2020.02.027

Rapid changes in expression of class I and IV histone deacetylases during epileptogenesis in mouse models of temporal lobe epilepsy

A spectrophotometer (Shimadzu UV-1700, Tokyo, Japan) was used to measure the optical density of the solution at 662 and 645 nm (for Ch a and b , respectively) and 470 nm (for TCAR)