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High-powered devices can deliver more nicotine per puff, potentially reducing the number of puffs needed to equal one cigarette

Participants with data linkage errors (n = 20, 0.01%), age below 45 years at baseline (n = 3, 0.001%), and missing or invalid data on smoking status (n = 860, 3%) were excluded

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Free base, salt nicotine, and nicotine-free (0mg) products are all available as long as they meet the 20mg/ml cap and hold ECAS approval