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And more women smoke Marlboro than any other brand

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In answer to the more direct question of how much nicotine per day is safe, a reasonable starting point might be, "How much nicotine might it take to poison someone?" The ECHA currently gives an "acute toxicity estimate" (ATE) for nicotine via the oral route to be 5 mg/kg bw [7] , meaning 5mg of nicotine for every kilogram of bodyweight of the person consuming the nicotine

These two tables are useful for physicians in identifying the clinical picture of patients presenting with EVALI: The patients tend to be younger males presenting with shortness of breath (85%), cough (85%), and subjective fever (84%)