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COMT (catechol-O-methyltransferase) gene variants that reduce prefrontal dopamine availability impair top-down inhibitory regulation of reward-seeking, increasing the probability that early gateway substance use will progress to compulsive drug-seeking behavior in the presence of substance availability

Robins Kaplan obtained a historic first in Tribal Government litigation, with a total of $1.5 billion in settlements obtained on behalf of the Tribal Nations

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