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Journal of Medicinal Chemistry

doi: 10.1186/s12944-016-0261-0 53 ShenYWanHZhuJFangZCheLXuSet al

Image analysis was performed with Zen 3.7 software (Zeiss)

Studies have shown that NF-B and MAPKs (three major kinases: JNK, p38 and ERK) are expressed in cultured RA-FLSs and easily activated by IL-1 and TNF- (210)