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In cells, H2O2 is also generated via several enzyme-mediated reactions, such as glycollate oxidase during photorespiration, acyl CoA oxidase during b-oxidation, oxalate oxidase that converts oxalate and oxygen to H2O2 and CO2, and NADPH oxidase (a plasma membrane located enzyme) that transfers electrons from NADPH to molecular oxygen to generate O2- (subsequently converted to H2O2) (Desikan et al., 2003)

In the light of ideas put forward by Parr et al., other new concepts contributing very important information about the response of a chemical species when it reacts with other chemical reagents were defined by several authors, including Gazquez [8-17]

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The big takeaway is simple: DSIP is not just a sleep pill. It sits at the crossroads of sleep stage timing, stress biology, and other body signals