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Animals developed persistent esophagitis with hemorrhagic lesions, thinned epithelium, and chronically reduced sphincter pressures lasting up to 20 months

The results showed that administration of CB significantly increased the abundance of SCFA-producing bacteria, relieved arterial lesions, and decreased the levels of inflammatory markers IL-1 and IL-6, whereas antibiotics depleted intestinal flora and exacerbated the inflammatory response (213)

Bactericidal means the substance actively kills bacteria

A simple rotation pattern like upper-left abdomen, upper-right, lower-left, lower-right gives you a four-week cycle before returning to the first site