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This change in the quantity of autophagosomes was overcome in cells pretreated with EVs-shVDAC1 ( Figure 4H )

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Pancreatic cancer studies have shown that broad depletion of stromal elements or carcinoma-associated fibroblasts can accelerate disease progression and worsen immunosuppression in some settings [70, 97]

Vincent A, Thauvin M, Quvrain E et al (2021) Evaluation of the compounds commonly known as superoxide dismutase and catalase mimics in cellular models