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Cardiovascular effects Combustible cigarette smoking is one of the strongest preventable risk factors for cardiovascular disease.[28] Though the association between e-cigarette use and cardiovascular outcomes is largely unclear at this point, new data suggest that e-cigarettes are associated with cardiovascular morbidity [Table 2], though it is likely less than that of combustible cigarette smoking.[29] This section highlights the potential associations between e-cigarette use and cardiovascular disease, hypertension, endothelial health, and myocardial function

Marijuana is still illegal at the federal level, so even states that have legalized it are left on their own when regulating its manufacture and sale