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Similar changes have been observed in the lung which is also characterized by evidence of increased oxidative stress including glutathione depletion, a shift to alternative methods of energy production, and reduced levels of ATP 15

An increased incidence of ataxia as a termination criterion could be observed with SHP099/trametinib/WA (Supplementary Fig

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Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase