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Transport of reduced form of cysteine has been assigned to the transporters form ASCT family

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IOC is a leading cause of mortality in individuals with chronic anemia-related disorders, such as -thalassemia and SCD, who undergo long-term transfusions, affecting approximately 2.5% of chronically transfusion-dependent SCD patients [19, 36, 41]

Risk Note: For example, Infusion studies in fetal sheep models found that high doses of IGF-1 LR3 were found to induced severe hypoglycemia and hypoxemia