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If pain becomes severe or persistent, evaluation for other causes like gallstones becomes necessary, as rapid weight loss increases cholecystitis risk

Why not just use sterile water Cost is the usual answer people give when they skip bacteriostatic water

In a co-administered protocol the three components depopulate at different rates from a single bolus, which is one of the legitimate criticisms of any fixed-ratio blend: the researcher cannot independently titrate frequency for the shorter-half-life components without also re-dosing the longer-half-life one